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- Keywords T cell receptor;Idiotype;DNA vaccine;Lymphoma;Antigen determinant; 细胞受体;独特型;DNA疫苗;淋巴瘤;抗原决定簇;
- Keywords T cell receptor repertoire;T cell activating threshold;functional avidity;immunization strategies; 关键词T细胞受体库;T细胞活化域值;功能亲和力;免疫方案;
- Marrack P, Kapler L. The T cell receptor[J]. Science, 1987,238:1073. 谢蜀生.;血细胞嵌合体与移植耐受[J]
- Objective To analyse the T cell receptor (TCR) gene rearrangement in myelodysplastic syndromes (MDS). 目的为了解骨髓增生异常综合征（MDS）患者T细胞受体（TCR）基因重排情况。
- The first signal is specific, which T cell receptor could recognize and bind MHC molecule by antigen presenting cells. 第二信号是由T细胞上的CD28与抗原呈递细胞上的B7分子的结合而提供的。
- Keywords Arthritis;rheumatoid;Synovium fluid;T cell receptor; 关节炎;类风湿;滑膜液;T细胞受体;
- Keywords T cell;superantigen;tumor; 细胞;超抗原;肿瘤;
- Keywords Immunological synapse;T cell receptor;Reorientation movement;Vortex; 免疫突触;T细胞受体;重定向运动;涡旋;
- CTLA-4, a second T cell receptor for B7, which is expressed on the surface ofactivated T cells, has been shown to play an inhibitory role in regulation of T cellresponses by preventing full T cell activation or terminating T cell responses. 细胞毒性T淋巴细胞相关抗原4（cytotoxic T lymphocyte associated antigen 4，CTLA-4），是共刺激分子B7的受体，主要表达于激活的T细胞表面，与B7结合后能抑制小鼠和人的T细胞的激活，在T细胞活化中起负调节作用。
- Objective To quantitative analysis the T cell receptor excision DNA circles (TRECs) in CD3 +, CD4 + or CD8 + T cells, evaluating the thymic recent output function in patients with chronic myelogenous leukemia (CML). 目的 了解慢性粒细胞白血病 (CML)患者CD3+ 、CD4 + 和CD8+ 细胞中T细胞受体重排删除DNA环 (TRECs)的含量 ,从而推测CML患者的胸腺近期输出功能。
- Methods Quantitative detection of T cell receptor excision DNA circles (TRECs) in DNA of peripheral blood mononuclear cells from 8 cases with CML, CD4 + or CD8 + cells from 3 cases with CML were preformed by real time PCR (TaqMan) analysis. 方法 利用实时定量PCR(Taq Man)方法检测 8例CML患者外周血单个核细胞、3例CML患者CD4 + 和CD8+ 细胞中TRECs的水平。
- T cell receptor rearrangement excision circles T细胞受体删除环
- T cell receptor rearrangement excisioncircles T细胞受体重排删除环
- Keywords T cell subsets;monoclonal antibody;McAb;breast cancer.; 细胞亚群;单克隆抗体;乳腺癌;
- Keywords T cell;allogeneic transplantation;immune tolerance;chimerism; 细胞;同种异基因移植;免疫耐受;嵌合体;
- T cell receptor rearrangement excision circles ( TRECs ) T细胞受体重排删除环
- Keywords chronic abacterial prostatitis/chronic pelvic pain syndrome;T cell receptor; 慢性非细菌性前列腺炎/慢性骨盆疼痛综合征;T细胞受体;
- Through the T cells receptors (TCRs), CTLs can recognize the MHC class I-associated peptides complex on surface of the antigen presenting cells (APCs) such as malignant cells. CTL通过其T细胞受体特异性识别抗原提呈细胞(antigen-presenting cells,APCs)(如肿瘤细胞)表面的主要组织相容性复合体(major histocompatibility complex, MHC)-I类分子-肽复合物,然后自身得以活化,并最终通过多种机制杀死靶细胞。
- Many scientists suspected that although the shape of MHC molecules varies between individuals, they might share some similarity that T cells receptors could recognize. 许多科学家推测尽管两个体间MHC分子形状差异，他们也许共同拥有为T细胞识别的一些类似之处。
